Defective clearance of nucleosomes and systemic lupus erythematosus

Y Maekawa, K Yasutomo - TRENDS in Immunology, 2001 - cell.com
Y Maekawa, K Yasutomo
TRENDS in Immunology, 2001cell.com
We reported recently a mutation in the DNASE1 gene in two patients with SLE (Ref. 2).
Therefore, we would like to review briefly the evidence for a link between the defective
clearance of apoptotic bodies or cells and this disease, provided by our data and other
animal models3, 4.
We reported recently a mutation in the DNASE1 gene in two patients with SLE (Ref. 2). Therefore, we would like to review briefly the evidence for a link between the defective clearance of apoptotic bodies or cells and this disease, provided by our data and other animal models3, 4.
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