[HTML][HTML] Lifetime of plasma cells in the bone marrow

RA Manz, A Thiel, A Radbruch - Nature, 1997 - nature.com
RA Manz, A Thiel, A Radbruch
Nature, 1997nature.com
Immune protection is based on long-lived memory cells and effector cells, which are either
cytotoxic or secrete antibodies. The lifespan of these effector cells has not so far been
determined. Here we show that antibody-secreting plasma cells from bone marrow are as
long-lived as memory B cells.
Abstract
Immune protection is based on long-lived memory cells and effector cells, which are either cytotoxic or secrete antibodies. The lifespan of these effector cells has not so far been determined. Here we show that antibody-secreting plasma cells from bone marrow are as long-lived as memory B cells.
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