A subset of viral transcripts packaged within human cytomegalovirus particles
WA Bresnahan, T Shenk - Science, 2000 - science.org
WA Bresnahan, T Shenk
Science, 2000•science.orgA human cytomegalovirus gene array was used to identify a previously unidentified class of
viral transcripts. These transcripts, termed virion RNAs, were packaged within infectious
virions and were delivered to the host cell on infection. This mechanism of herpesvirus gene
expression allows for viral genes to be expressed within an infected cell immediately after
virus entry and in the absence of transcription from the viral genome.
viral transcripts. These transcripts, termed virion RNAs, were packaged within infectious
virions and were delivered to the host cell on infection. This mechanism of herpesvirus gene
expression allows for viral genes to be expressed within an infected cell immediately after
virus entry and in the absence of transcription from the viral genome.
A human cytomegalovirus gene array was used to identify a previously unidentified class of viral transcripts. These transcripts, termed virion RNAs, were packaged within infectious virions and were delivered to the host cell on infection. This mechanism of herpesvirus gene expression allows for viral genes to be expressed within an infected cell immediately after virus entry and in the absence of transcription from the viral genome.
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