The kit ligand, stem cell factor
SJ Galli, KM Zsebo, EN Geissler - Advances in immunology, 1993 - Elsevier
Publisher Summary This chapter focuses on the importance of stem cell factor (SCF) and the
stem cell factor receptor (SCFR) in hematopoiesis and other complex developmental
programs affecting melanocytes, germ cells, and mast cells that are predicted based on an
analysis of the phenotype of mice with mutations affecting SCF or its receptor. Investigation
of the effects of SCF on a single cell type, the mast cell, has produced the most complete
picture of the spectrum of biological processes that can be regulated by interactions …
stem cell factor receptor (SCFR) in hematopoiesis and other complex developmental
programs affecting melanocytes, germ cells, and mast cells that are predicted based on an
analysis of the phenotype of mice with mutations affecting SCF or its receptor. Investigation
of the effects of SCF on a single cell type, the mast cell, has produced the most complete
picture of the spectrum of biological processes that can be regulated by interactions …