Interferons modulate FcɛRI-dependent production of autoregulatory IL-10 by circulating human monocytoid dendritic cells

T Le, J Tversky, KL Chichester, AP Bieneman… - Journal of allergy and …, 2009 - Elsevier
BACKGROUND: Immature human blood monocytoid dendritic cells (mDCs) express high-
affinity receptors for IgE (FcɛRI), yet their exact function and regulation remain poorly
understood. OBJECTIVE: We sought to characterize FcɛRI-dependent cytokine responses
and their regulation in circulating human blood mDCs. METHODS: FcɛRI-dependent
cytokine responses of circulating mDCs were studied by using anti-FcɛRIα stimulation.
Plasmacytoid dendritic cell (pDC) cross-regulation through Toll-like receptor 9 on these …