Interferon γ (IFNγ) plays a central role in the immune response against infection and tumur
immune surveillance. Its functions include not only activation of the host immune system to
control microbial infections but also repression of autoimmune responses by turning on T-
regulatory cells and increasing T effector cell apoptosis. Defects in IFNγ and IFNγ receptor
genes have been associated with autoimmune diseases such as rheumatoid arthritis, type 1
diabetes and multiple sclerosis. However, treatment of autoimmune diseases by …