Genetically elevated lipoprotein (a) and increased risk of myocardial infarction

PR Kamstrup, A Tybjaerg-Hansen, R Steffensen… - Jama, 2009 - jamanetwork.com
Context High levels of lipoprotein (a) are associated with increased risk of myocardial
infarction (MI). Objective To assess whether genetic data are consistent with this association
being causal. Design, Setting, and Participants Three studies of white individuals from
Copenhagen, Denmark, were used: the Copenhagen City Heart Study (CCHS), a
prospective general population study with 16 years of follow-up (1991-2007, n= 8637, 599
MI events); the Copenhagen General Population Study (CGPS), a cross-sectional general …