Lipoprotein (a): intrigues and insights
HH Hobbs, AL White - Current opinion in lipidology, 1999 - journals.lww.com
HH Hobbs, AL White
Current opinion in lipidology, 1999•journals.lww.comLipoprotein (a) is an atherogenic, cholesterol ester-rich lipoprotein of unknown physiological
function. The unusual species distribution of lipoprotein (a) and the extreme polymorphic
nature of its distinguishing apolipoprotein component, apolipoprotein (a), have provided
unique challenges for the investigation of its biochemistry, genetics, metabolism and
atherogenicity. Some fundamental questions regarding this enigmatic lipoprotein have
escaped elucidation, as will be highlighted in this review.
function. The unusual species distribution of lipoprotein (a) and the extreme polymorphic
nature of its distinguishing apolipoprotein component, apolipoprotein (a), have provided
unique challenges for the investigation of its biochemistry, genetics, metabolism and
atherogenicity. Some fundamental questions regarding this enigmatic lipoprotein have
escaped elucidation, as will be highlighted in this review.
Abstract
Lipoprotein (a) is an atherogenic, cholesterol ester-rich lipoprotein of unknown physiological function. The unusual species distribution of lipoprotein (a) and the extreme polymorphic nature of its distinguishing apolipoprotein component, apolipoprotein (a), have provided unique challenges for the investigation of its biochemistry, genetics, metabolism and atherogenicity. Some fundamental questions regarding this enigmatic lipoprotein have escaped elucidation, as will be highlighted in this review.
Lippincott Williams & Wilkins