Current animal models of antipsychotic activity that have the capacity to dissociate between
typical and atypical antipsychotic drugs (APDs) have two drawbacks: they require previous
administration of a psychotomimetic drug, and they achieve the dissociation by
demonstrating effectiveness of atypical but not typical APDs, thus losing specificity and
selectivity for APDs. The present experiments were designed to solve these problems by
using two non-pharmacological tests: latent inhibition (LI), in which potentiation of the …