Acute psychological stress raises plasma ghrelin in the rat

E Kristenssson, M Sundqvist, M Astin, M Kjerling… - Regulatory peptides, 2006 - Elsevier
Ghrelin is produced by the A-like cells of the stomach and mobilized by food deprivation. It
was reported recently that acute psychological stress increases ghrelin gene expression in
rat oxyntic mucosa. The aim of this study was to examine the effect of such stress on
circulating ghrelin levels. To this end, we measured plasma ghrelin in Wistar Kyoto (WKY)
rats (a high-anxiety strain) and Sprague–Dawley (SPD) rats (a low-anxiety strain), exposed
to water avoidance stress for 60 min. Blood was collected before and after the stress. Acute …