The CCK (-like) receptor in the animal kingdom: functions, evolution and structures

D Staljanssens, EK Azari, O Christiaens, J Beaufays… - Peptides, 2011 - Elsevier
In this review, the cholecystokinin (CCK)(-like) receptors throughout the animal kingdom are
compared on the level of physiological functions, evolutionary basis and molecular structure.
In vertebrates, the CCK receptor is an important member of the G-protein coupled receptors
as it is involved in the regulation of many physiological functions like satiety, gastrointestinal
motility, gastric acid secretion, gall bladder contraction, pancreatic secretion, panic, anxiety
and memory and learning processes. A homolog for this receptor is also found in nematodes …