Myeloid and plasmacytoid dendritic cells in induced sputum after allergen inhalation in subjects with asthma
B Dua, RM Watson, GM Gauvreau… - Journal of Allergy and …, 2010 - Elsevier
BACKGROUND: Dendritic cells are professional antigen presenting cells that mediate the
response to inhaled allergens. In animal models, the induction and maintenance of allergic
airway inflammation is primarily a function of myeloid dendritic cells, whereas the tolerization
to inhaled allergens is likely a function of plasmacytoid dendritic cells. OBJECTIVE: To
investigate changes in sputum myeloid and plasmacytoid dendritic cells after allergen
inhalation in subjects with asthma. Also, the number of myeloid and plasmacytoid dendritic …
response to inhaled allergens. In animal models, the induction and maintenance of allergic
airway inflammation is primarily a function of myeloid dendritic cells, whereas the tolerization
to inhaled allergens is likely a function of plasmacytoid dendritic cells. OBJECTIVE: To
investigate changes in sputum myeloid and plasmacytoid dendritic cells after allergen
inhalation in subjects with asthma. Also, the number of myeloid and plasmacytoid dendritic …