The CC chemokine CCL20 and its receptor CCR6

E Schutyser, S Struyf, J Van Damme - Cytokine & growth factor reviews, 2003 - Elsevier
CCL20, alternatively named liver and activation-regulated chemokine (LARC), macrophage
inflammatory protein-3α (MIP-3α) or Exodus-1, is the only chemokine known to interact with
CC chemokine receptor 6 (CCR6), a property shared with the antimicrobial β-defensins. The
ligand-receptor pair CCL20-CCR6 is responsible for the chemoattraction of immature
dendritic cells (DC), effector/memory T-cells and B-cells and plays a role at skin and
mucosal surfaces under homeostatic and inflammatory conditions, as well as in pathology …