The ETS-domain transcription factor family
AD Sharrocks - Nature reviews Molecular cell biology, 2001 - nature.com
Nature reviews Molecular cell biology, 2001•nature.com
ETS-domain transcription-factor networks represent a model for how combinatorial gene
expression is achieved. These transcription factors interact with a multitude of co-regulatory
partners to elicit gene-specific responses and drive distinct biological processes. These
proteins are controlled by a complex series of inter and intramolecular interactions, and
signalling pathways impinge on these proteins to further regulate their action.
expression is achieved. These transcription factors interact with a multitude of co-regulatory
partners to elicit gene-specific responses and drive distinct biological processes. These
proteins are controlled by a complex series of inter and intramolecular interactions, and
signalling pathways impinge on these proteins to further regulate their action.
Abstract
ETS-domain transcription-factor networks represent a model for how combinatorial gene expression is achieved. These transcription factors interact with a multitude of co-regulatory partners to elicit gene-specific responses and drive distinct biological processes. These proteins are controlled by a complex series of inter and intramolecular interactions, and signalling pathways impinge on these proteins to further regulate their action.
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