[PDF][PDF] Fatty acid accumulation and abnormal lipid deposition in peripheral and border zones of experimental myocardial infarcts

DW Bilheimer, LM Buja, RW Parkey… - Journal of Nuclear …, 1978 - Soc Nuclear Med
DW Bilheimer, LM Buja, RW Parkey, FJ Bonte, JT Willerson
Journal of Nuclear Medicine, 1978Soc Nuclear Med
MATERIALSANDMETHODS Twenty-eight adult mongrel dogs were anesthetized with
pentobarbital(30 mg/kg) and their chests opened under sterile conditions. The proximal left
anterior descending coronary artery (LAD) was permanently ligated. A left atrial catheter was
in serted and its connection exteriorized. The dogs' chests were closed and they were
allowed to awaken. Preparation of radiolabeled materials. Dog albu mm (fraction V),[†4C]
oleic acid (54.5 mCi/cc), and [3HJ glycerol (200 mCi/cc) were obtained com mercially. The …
MATERIALSANDMETHODS
Twenty-eight adult mongrel dogs were anesthetized with pentobarbital(30 mg/kg) and their chests opened under sterile conditions. The proximal left anterior descending coronary artery (LAD) was permanently ligated. A left atrial catheter was in serted and its connection exteriorized. The dogs' chests were closed and they were allowed to awaken. Preparation of radiolabeled materials. Dog albu mm (fraction V),[†4C] oleic acid (54.5 mCi/cc), and [3HJ glycerol (200 mCi/cc) were obtained com mercially. The canine albumin-[14C] oleate complex was prepared by the method of Van Harkin et al.
Society of Nuclear Medicine and Molecular Imaging