Vascular abnormalities, paraoxonase activity, and dysfunctional HDL in primary antiphospholipid syndrome
M Charakida, C Besler, JR Batuca, S Sangle… - Jama, 2009 - jamanetwork.com
Context Accelerated atherosclerosis has been described in antiphospholipid syndrome, but
the vascular abnormalities and the underlying mechanisms remain unclear. Objectives To
compare vascular structure and function in patients with positive antiphospholipid antibodies
(aPL) with controls and to assess their relationship with paraoxonase activity. Design,
Setting, and Participants A cross-sectional study of 77 women with positive antiphospholipid
antibodies from a lupus outpatient clinic in London, England (90% of the eligible population) …
the vascular abnormalities and the underlying mechanisms remain unclear. Objectives To
compare vascular structure and function in patients with positive antiphospholipid antibodies
(aPL) with controls and to assess their relationship with paraoxonase activity. Design,
Setting, and Participants A cross-sectional study of 77 women with positive antiphospholipid
antibodies from a lupus outpatient clinic in London, England (90% of the eligible population) …