[HTML][HTML] Molecular regulation of HDL metabolism and function: implications for novel therapies
DJ Rader - The Journal of clinical investigation, 2006 - Am Soc Clin Investig
DJ Rader
The Journal of clinical investigation, 2006•Am Soc Clin InvestigHDL metabolism represents a major target for the development of therapies intended to
reduce the risk of atherosclerotic cardiovascular disease. HDL metabolism is complex and
involves dissociation of HDL apolipoprotein and HDL cholesterol metabolism. Advances in
our understanding of the molecular regulation of HDL metabolism, macrophage cholesterol
efflux, and HDL function will lead to a variety of novel therapeutics.
reduce the risk of atherosclerotic cardiovascular disease. HDL metabolism is complex and
involves dissociation of HDL apolipoprotein and HDL cholesterol metabolism. Advances in
our understanding of the molecular regulation of HDL metabolism, macrophage cholesterol
efflux, and HDL function will lead to a variety of novel therapeutics.
HDL metabolism represents a major target for the development of therapies intended to reduce the risk of atherosclerotic cardiovascular disease. HDL metabolism is complex and involves dissociation of HDL apolipoprotein and HDL cholesterol metabolism. Advances in our understanding of the molecular regulation of HDL metabolism, macrophage cholesterol efflux, and HDL function will lead to a variety of novel therapeutics.
The Journal of Clinical Investigation