Changes in NK cell activity during the estrous cycle and pregnancy in mice
K Furukawa, K Itoh, K Okamura, K Kumagai… - Journal of reproductive …, 1984 - Elsevier
Abstract Changes in NK cell activity during the estrous cycle and pregnancy in mice were
studied by a 4 h 51 Cr-release assay using YAC-1 cells as a target. NK activity both in the
spleen and peripheral blood mononuclear cells showed a single fluctuation with a peak at
met-estrous-2 during the estrous cycle. Splenic NK activity was suppressed in the early to
mid-stages of pregnancy but increased sharply in the late stage. The activity declined
thereafter, reaching the estrous level post-partum. NK activity in the peripheral blood …
studied by a 4 h 51 Cr-release assay using YAC-1 cells as a target. NK activity both in the
spleen and peripheral blood mononuclear cells showed a single fluctuation with a peak at
met-estrous-2 during the estrous cycle. Splenic NK activity was suppressed in the early to
mid-stages of pregnancy but increased sharply in the late stage. The activity declined
thereafter, reaching the estrous level post-partum. NK activity in the peripheral blood …