Preparation of cell-wall fractions from mycobacteria
GS Besra - Mycobacteria protocols, 1998 - Springer
Mycobacteria protocols, 1998•Springer
Research extending over 50 years has implicated various components of the mycobacterial
cell-wall matrix in many host responses associated with tuberculosis and other
mycobacterioses (1). The observed responses originally included granuloma formation, high-
titer IgG antibodies, and the state of the T cell-mediated immunological anergy evident in
multibacillary leprosy and, more recently, in the induction of specific cytokines, phagocytosis
of the organism, cellular refractivity to cytokine stimulation, and regulation of phagosome …
cell-wall matrix in many host responses associated with tuberculosis and other
mycobacterioses (1). The observed responses originally included granuloma formation, high-
titer IgG antibodies, and the state of the T cell-mediated immunological anergy evident in
multibacillary leprosy and, more recently, in the induction of specific cytokines, phagocytosis
of the organism, cellular refractivity to cytokine stimulation, and regulation of phagosome …
Abstract
Research extending over 50 years has implicated various components of the mycobacterial cell-wall matrix in many host responses associated with tuberculosis and other mycobacterioses (1). The observed responses originally included granuloma formation, high-titer IgG antibodies, and the state of the T cell-mediated immunological anergy evident in multibacillary leprosy and, more recently, in the induction of specific cytokines, phagocytosis of the organism, cellular refractivity to cytokine stimulation, and regulation of phagosome-lysosome fusion.
Springer