Characterization of somatic Ca2+ clearance mechanisms in young and mature hippocampal granule cells

SH Lee, WK Ho, SH Lee - Cell calcium, 2009 - Elsevier
Calcium is a key regulator for expression of genes relevant to survival and maturation of
newborn neurons. Mammalian hippocampal dentate gyrus generates new granule cells
(GCs) throughout adult life. We identified young and mature GCs in hippocampi of young
adult mice according to their electrical properties, and investigated contributions of Na/Ca
exchanger (NCX), sarco-endoplasmic reticulum Ca2+-ATPase (SERCA), plasma membrane
Ca2+-ATPase (PMCA) and mitochondria to Ca2+ clearance in somata of GCs. Somatic …