Effect of gastrointestinal peptides on ingestion in old and young mice
AJ Silver, JF Flood, JE Morley - Peptides, 1988 - Elsevier
Early satiety may play a role in the anorexia of aging. The effects of the peripheral satiety
agents cholecystokinin (CCK), bombesin, glucagon, and calcitonin were studied in 8 and 25
month old mice. During normal feeding behavior, the older mice consumed more than their
younger counterparts, however, when food deprived, the younger consumed more. All
peptides inhibited food intake over the first hour after administration in young and old mice.
CCK, bombesin, and calcitonin suppressed feeding in 25 month old mice to a greater extent …
agents cholecystokinin (CCK), bombesin, glucagon, and calcitonin were studied in 8 and 25
month old mice. During normal feeding behavior, the older mice consumed more than their
younger counterparts, however, when food deprived, the younger consumed more. All
peptides inhibited food intake over the first hour after administration in young and old mice.
CCK, bombesin, and calcitonin suppressed feeding in 25 month old mice to a greater extent …