Unraveling the science of incretin biology

MA Nauck - European journal of internal medicine, 2009 - Elsevier
Type 2 diabetes mellitus has become an enormous and worldwide healthcare problem that
is almost certain to worsen. Current therapies, which address glycemia and insulin
resistance, have not adequately addressed the complications and treatment failures
associated with this disease. New treatments based on the incretin hormones provide a
novel approach to address some components of the complex pathophysiology of type 2
diabetes. The purpose of this review is to elucidate the science of the incretin hormones and …