Interplay between obesity and associated metabolic disorders: new insights into the gut microbiota

PD Cani, NM Delzenne - Current opinion in pharmacology, 2009 - Elsevier
Obesity and associated metabolic disorders are worldwide epidemic. The literature provides
new evidence that gut microbiota dysbiosis (at the phyla, genus, or species level) affects
host metabolism and energy storage. Here we discuss new findings that may explain how
gut microbiota can be involved in the development or in the control of obesity and
associated low-grade inflammation. New powerful molecular biology methods and the use
of gnotobiotic animal allowed to analyze the molecular link between gut bacteria and the …