Intestinal nutrient transport in genetically obese mice

RP Ferraris, RR Vinnakota - The American journal of clinical nutrition, 1995 - Elsevier
The small intestine of obese animals supplies nutrients to a metabolic live mass (body
weight 0.75) that is much higher than that of age-and sex-matched lean animals. To
determine the mechanisms of adaptation of the small intestine to obesity, we determined the
rate of uptake of D-glucose and five amino acids, the site density of intestinal D-glucose
transporters, and the permeability of the absorptive mucosa in isolated everted intestinal
sleeves of genetically obese male mice (C57BL/6J ob/ob) and their lean male littermates …