Cystic lung disease in Birt-Hogg-Dube syndrome
Background To describe the clinical, radiologic, and histopathologic aspects of cystic lung
disease occurring in patients with Birt-Hogg-Dubé (BHD) syndrome, a rare, inheritable,
multisystem disorder. Methods We retrospectively reviewed five patients with BHD syndrome
evaluated at the Mayo Clinic Rochester from 1998 through 2005. Results Mean age (±SD) at
the time of pulmonary evaluation was 56.4±4.8 years; four patients were men. Three patients
had not received a diagnosis of BHD syndrome at the time of initial CT of the chest. Three …
disease occurring in patients with Birt-Hogg-Dubé (BHD) syndrome, a rare, inheritable,
multisystem disorder. Methods We retrospectively reviewed five patients with BHD syndrome
evaluated at the Mayo Clinic Rochester from 1998 through 2005. Results Mean age (±SD) at
the time of pulmonary evaluation was 56.4±4.8 years; four patients were men. Three patients
had not received a diagnosis of BHD syndrome at the time of initial CT of the chest. Three …