Matrix metalloproteinase-9 polymorphism and risk of pelvic organ prolapse in Taiwanese women

HY Chen, WY Lin, YH Chen, WC Chen, FJ Tsai… - European Journal of …, 2010 - Elsevier
OBJECTIVE: Matrix metalloproteinase-9 is known to play an important role in the
pathophysiology of pelvic organ prolapse. We investigated whether the matrix
metalloproteinase-9 gene polymorphisms were associated with pelvic organ prolapse by
conducting a case–control association study in 92 women with pelvic organ prolapse and
152 women without pelvic organ prolapse. STUDY DESIGN: Genotypes of the matrix
metalloproteinase-9 gene polymorphisms (rs3918242, rs17576, and rs2250889) were …