The transmembrane glycoprotein CD98 regulates multiple cellular functions, including
extracellular signaling, epithelial cell adhesion/polarity, amino acid transport, and cell-cell
interactions. MicroRNAs post-transcriptionally regulate gene expression, thereby functioning
as modulators of numerous cellular processes, such as cell differentiation, proliferation, and
apoptosis. Here, we investigated if microRNAs regulate CD98 expression during intestinal
epithelial cell differentiation and inflammation. We found that microRNA-7 repressed CD98 …