[PDF][PDF] Metastasis-promoting immunity: when T cells turn to the dark side
D Pardoll - Cancer cell, 2009 - cell.com
Cancer cell, 2009•cell.com
While the role of endogenous T cells in antitumor immunity is being debated, little is known
about whether and how T cells promote tumorigenesis. In this issue of Cancer Cell,
DeNardo and colleagues demonstrate that IL-4-producing T cells enhance metastasis by
programming macrophages to produce factors that enhance tumor invasion.
about whether and how T cells promote tumorigenesis. In this issue of Cancer Cell,
DeNardo and colleagues demonstrate that IL-4-producing T cells enhance metastasis by
programming macrophages to produce factors that enhance tumor invasion.
While the role of endogenous T cells in antitumor immunity is being debated, little is known about whether and how T cells promote tumorigenesis. In this issue of Cancer Cell, DeNardo and colleagues demonstrate that IL-4-producing T cells enhance metastasis by programming macrophages to produce factors that enhance tumor invasion.
cell.com