[HTML][HTML] miRNAs get an early start on translational silencing
G Meister - Cell, 2007 - cell.com
Cell, 2007•cell.com
MicroRNAs (miRNAs) control gene expression by regulating mRNA stability and translation.
Using cell-free in vitro systems, several labs have recently reported insights into the
molecular mechanisms underlying miRNA-guided translational repression (Kiriakidou et al.,
2007; Mathonnet et al., 2007; Thermann and Hentze, 2007; Wakiyama et al., 2007). These
new findings indicate that miRNAs inhibit translation at early steps of initiation.
Using cell-free in vitro systems, several labs have recently reported insights into the
molecular mechanisms underlying miRNA-guided translational repression (Kiriakidou et al.,
2007; Mathonnet et al., 2007; Thermann and Hentze, 2007; Wakiyama et al., 2007). These
new findings indicate that miRNAs inhibit translation at early steps of initiation.
MicroRNAs (miRNAs) control gene expression by regulating mRNA stability and translation. Using cell-free in vitro systems, several labs have recently reported insights into the molecular mechanisms underlying miRNA-guided translational repression (Kiriakidou et al., 2007; Mathonnet et al., 2007; Thermann and Hentze, 2007; Wakiyama et al., 2007). These new findings indicate that miRNAs inhibit translation at early steps of initiation.
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