Hay fever and asthma in relation to markers of infection in the United States
PM Matricardi, F Rosmini, V Panetta, L Ferrigno… - Journal of Allergy and …, 2002 - Elsevier
Background: The hygiene hypothesis proposes that declining exposure to infections is
implicated in the rising trend of allergy and asthma. Objective: We sought to test this
hypothesis by examining the relationship of hay fever, asthma, and atopic sensitization with
markers of infection in a large general population sample of the United States. Methods: We
analyzed the data of 33,994 US residents recorded in a public database of a nationally
representative cross-sectional survey (Third National Health and Nutrition Examination …
implicated in the rising trend of allergy and asthma. Objective: We sought to test this
hypothesis by examining the relationship of hay fever, asthma, and atopic sensitization with
markers of infection in a large general population sample of the United States. Methods: We
analyzed the data of 33,994 US residents recorded in a public database of a nationally
representative cross-sectional survey (Third National Health and Nutrition Examination …