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URL: http://scholar.google.com/scholar_lookup?title=The+tyrosine+phosphatase+SHP-2+is+required+for+mediating+phosphatidylinositol+3-kinase%2FAkt+activation+by+growth+factors.&year=2001&author=Wu&journal=Oncogene.&volume=20&issue=42&pages=6018-6025&doi=10.1038%2Fsj.onc.1204699&pmid=11593409