Long Polar Fimbriae Contribute to Colonization by Escherichia coli O157:H7 In Vivo

DM Jordan, N Cornick, AG Torres… - Infection and …, 2004 - Am Soc Microbiol
DM Jordan, N Cornick, AG Torres, EA Dean-Nystrom, JB Kaper, HW Moon
Infection and immunity, 2004Am Soc Microbiol
The contribution of long polar fimbriae to intestinal colonization by Escherichia coli O157: H7
was evaluated in sheep, conventional pigs, and gnotobiotic piglets. E. coli O157: H7 strains
with lpfA1 and lpfA2 mutated were recovered in significantly lower numbers and caused
fewer attachment and effacement lesions than the parent strain.
Abstract
The contribution of long polar fimbriae to intestinal colonization by Escherichia coli O157:H7 was evaluated in sheep, conventional pigs, and gnotobiotic piglets. E. coli O157:H7 strains with lpfA1 and lpfA2 mutated were recovered in significantly lower numbers and caused fewer attachment and effacement lesions than the parent strain.
American Society for Microbiology