Allergy or tolerance in children sensitized to peanut: prevalence and differentiation using component-resolved diagnostics

N Nicolaou, M Poorafshar, C Murray, A Simpson… - Journal of Allergy and …, 2010 - Elsevier
BACKGROUND: Not all peanut-sensitized children develop allergic reactions on exposure.
OBJECTIVE: To establish by oral food challenge the proportion of children with clinical
peanut allergy among those considered peanut-sensitized by using skin prick tests and/or
IgE measurement, and to investigate whether component-resolved diagnostics using
microarray could differentiate peanut allergy from tolerance. METHODS: Within a population-
based birth cohort, we ascertained peanut sensitization by skin tests and IgE measurement …