Detection of herpesvirus type 8 (HHV8) in children's tonsils and adenoids by immunohistochemistry and in situ hybridization

CA Chagas, LH Endo, E Sakano, GA Pinto… - International journal of …, 2006 - Elsevier
OBJECTIVE: Human herpesvirus 8 (HHV8) has been associated with multicentric
Castleman's disease, Kaposi's sarcoma and effusion non-Hodgkin's lymphoma.
Epidemiological studies have shown seropositivity in variable proportions of populations. It
seems to be sexually transmitted among adults and through oral contact among children.
The virus has been demonstrated in desquamating oral epithelial cells, but there is no report
on its presence in the Waldeyer's ring. The purpose of the present study is to detect HHV8 in …