Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6.
KA Lord, B Hoffman-Liebermann, DA Liebermann - Oncogene, 1990 - europepmc.org
KA Lord, B Hoffman-Liebermann, DA Liebermann
Oncogene, 1990•europepmc.orgWe report here the full length cDNA sequence and the deduced amino-acid sequence of
MyD88, a novel myeloid differentiation primary response gene activated in M1D+ myeloid
precursors, following induction of terminal differentiation and growth arrest by IL6.
Detectable levels of MyD88 RNA were observed in myeloid precursor enriched murine bone-
marrow, but not in several other non-myeloid murine tissues.
MyD88, a novel myeloid differentiation primary response gene activated in M1D+ myeloid
precursors, following induction of terminal differentiation and growth arrest by IL6.
Detectable levels of MyD88 RNA were observed in myeloid precursor enriched murine bone-
marrow, but not in several other non-myeloid murine tissues.
We report here the full length cDNA sequence and the deduced amino-acid sequence of MyD88, a novel myeloid differentiation primary response gene activated in M1D+ myeloid precursors, following induction of terminal differentiation and growth arrest by IL6. Detectable levels of MyD88 RNA were observed in myeloid precursor enriched murine bone-marrow, but not in several other non-myeloid murine tissues.
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