Serial changes of cerebral glucose metabolism and caudate size in persons at risk for Huntington's disease
ST Grafton, JC Mazziotta, JJ Pahl… - Archives of …, 1992 - jamanetwork.com
• Objective.—To determine the rate of change of glucose metabolism and caudate size in
persons at risk for Huntington's disease. Design.—Eighteen persons at risk for Huntington's
disease had two positron emission tomographic glucose metabolic studies and two
magnetic resonance imaging scans separated by 42 (±9) months. Setting.—Ambulatory
research subjects at a teaching hospital with magnetic resonance imaging and positron
emission tomographic technology. Subjects.—Seven of the individuals were …
persons at risk for Huntington's disease. Design.—Eighteen persons at risk for Huntington's
disease had two positron emission tomographic glucose metabolic studies and two
magnetic resonance imaging scans separated by 42 (±9) months. Setting.—Ambulatory
research subjects at a teaching hospital with magnetic resonance imaging and positron
emission tomographic technology. Subjects.—Seven of the individuals were …