Striatal and white matter predictors of estimated diagnosis for Huntington disease
JS Paulsen, PC Nopoulos, E Aylward, CA Ross… - Brain research …, 2010 - Elsevier
Previous MRI studies with participants prior to manifest Huntington disease have been
conducted in small single-site samples. The current study reports data from a systematic
multi-national study during the prodromal period of Huntington disease and examines
whether various brain structures make unique predictions about the proximity to manifest
disease. MRI scans were acquired from 657 participants enrolled at 1 of 32 PREDICT-HD
research sites. Only prodromal Huntington disease participants (those not meeting motor …
conducted in small single-site samples. The current study reports data from a systematic
multi-national study during the prodromal period of Huntington disease and examines
whether various brain structures make unique predictions about the proximity to manifest
disease. MRI scans were acquired from 657 participants enrolled at 1 of 32 PREDICT-HD
research sites. Only prodromal Huntington disease participants (those not meeting motor …