Dual role of Nr2e3 in photoreceptor development and maintenance
AL Webber, P Hodor, CJ Thut, TF Vogt, T Zhang… - Experimental Eye …, 2008 - Elsevier
Nr2e3 is a photoreceptor-specific nuclear receptor believed to play a role in photoreceptor
development, differentiation, and survival. Much research has focused on the interaction of
Nr2e3 with other transcription factors in determining the milieu of target gene expression in
photoreceptors of the neonatal and adult retina. To investigate the downstream targets of
Nr2e3 and thereby shed light on the functional pathways relevant to photoreceptor
development and maintenance, expression profiling was performed on retinas from two …
development, differentiation, and survival. Much research has focused on the interaction of
Nr2e3 with other transcription factors in determining the milieu of target gene expression in
photoreceptors of the neonatal and adult retina. To investigate the downstream targets of
Nr2e3 and thereby shed light on the functional pathways relevant to photoreceptor
development and maintenance, expression profiling was performed on retinas from two …