Secondary sexual characteristics and menses in young girls seen in office practice: a study from the Pediatric Research in Office Settings network

ME Herman-Giddens, EJ Slora, RC Wasserman… - …, 1997 - publications.aap.org
Objective. To determine the current prevalence and mean ages of onset of pubertal
characteristics in young girls seen in pediatric practices in the United States. Methods. A
cross-sectional study was conducted by 225 clinicians in pediatric practices belonging to
Pediatric Research in Office Settings, a practice-based research network. After standardized
training in the assessment of pubertal maturation, practitioners rated the level of sexual
maturation on girls 3 through 12 years who were undergoing complete physical …