Leptin effects on pulsatile gonadotropin releasing hormone secretion from the adult rat hypothalamus and interaction with cocaine and amphetamine regulated …
AS Parent, MC Lebrethon, A Gérard… - Regulatory peptides, 2000 - Elsevier
Leptin may act as a negative feedback signal to the hypothalamic control of appetite through
suppression of neuropeptide Y (NPY) secretion and stimulation of cocaine and
amphetamine regulated transcript (CART). We aimed at studying the effects of leptin, CART
and NPY on the hypothalamic control of the pituitary–gonadal system. Pulsatile
gonadotropin-releasing hormone (GnRH) secretion was studied in vitro using
retrochiasmatic hypothalamic explants from adult rats. In the female, GnRH pulse amplitude …
suppression of neuropeptide Y (NPY) secretion and stimulation of cocaine and
amphetamine regulated transcript (CART). We aimed at studying the effects of leptin, CART
and NPY on the hypothalamic control of the pituitary–gonadal system. Pulsatile
gonadotropin-releasing hormone (GnRH) secretion was studied in vitro using
retrochiasmatic hypothalamic explants from adult rats. In the female, GnRH pulse amplitude …