Studies on the blood-brain barrier: I. The basis of dosage for animals of various weights

OL Davies, EW Hurst - British Journal of Pharmacology and …, 1948 - ncbi.nlm.nih.gov
OL Davies, EW Hurst
British Journal of Pharmacology and Chemotherapy, 1948ncbi.nlm.nih.gov
STUDIES ON THE BLOOD-BRAIN BARRIER I. THE BASIS OF DOSAGE FOR ANIMALS OF
VARIOUS WEIGHTS Page 1 Brit. J. Pharinacol. (1948), 3, 309. STUDIES ON THE BLOOD-BRAIN
BARRIER I. THE BASIS OF DOSAGE FOR ANIMALS OF VARIOUS WEIGHTS BY 0. L. DAVIES
AND E. WESTON HURST From Imperial Chemical Industries Limited, Biological Laboratories,
Hexagon House, Manchester, 9 (Received June 1. According to common belief, the cerebral
blood- relative to the body-weight is enormously greater vessels are more permeable in the …
METHODS Mice were selected according to weight. The weight of a mouse is a fairly precise indication of its age only if conditions of maintenance have been standardized and, at any rate in younger mice, the sizes of the litters
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