The growth of blood and lymphatic vessels, namely angiogenesis and lymphangiogenesis,
is well known to be of importance for tumor growth and metastatic spread. In fact, several
therapeutic strategies are currently being pursued in the clinic to interfere with these
processes. By contrast, vascular remodeling associated with chronic inflammatory disorders,
such as psoriasis, rheumatoid arthritis or inflammatory bowel disease, is only now emerging
as a potential new target to treat these conditions. Animal models of inflammation, which …