Assessment of FIBROSpect II to detect hepatic fibrosis in chronic hepatitis C patients
A Zaman, HR Rosen, K Ingram, CL Corless… - The American journal of …, 2007 - Elsevier
BACKGROUND: The degree of liver fibrosis in patients with Hepatitis C (HCV) provides
important prognostic information; however, the only current method available to obtain this
information is by performing a liver biopsy. Liver biopsies are invasive, associated with
complications, and costly. There has been recent interest in developing a panel of serum
markers that can reliably predict the presence of fibrosis and, thus, obviate the need for a
liver biopsy. Our objective was to prospectively validate a panel of serum fibrosis markers …
important prognostic information; however, the only current method available to obtain this
information is by performing a liver biopsy. Liver biopsies are invasive, associated with
complications, and costly. There has been recent interest in developing a panel of serum
markers that can reliably predict the presence of fibrosis and, thus, obviate the need for a
liver biopsy. Our objective was to prospectively validate a panel of serum fibrosis markers …