Human cytomegalovirus reinfection is associated with intrauterine transmission in a highly cytomegalovirus-immune maternal population
OBJECTIVE: To determine contribution of reinfection with new strains of cytomegalovirus in
cytomegalovirus seromimmune women to incidence of congenital cytomegalovirus infection.
STUDY DESIGN: In 7848 women studied prospectively for congenital cytomegalovirus
infection from a population with near universal cytomegalovirus seroimmunity, sera from 40
mothers of congenitally infected infants and 109 mothers of uninfected newborns were
analyzed for strain-specific anticytomegalovirus antibodies. RESULTS: All women were …
cytomegalovirus seromimmune women to incidence of congenital cytomegalovirus infection.
STUDY DESIGN: In 7848 women studied prospectively for congenital cytomegalovirus
infection from a population with near universal cytomegalovirus seroimmunity, sera from 40
mothers of congenitally infected infants and 109 mothers of uninfected newborns were
analyzed for strain-specific anticytomegalovirus antibodies. RESULTS: All women were …