Cytomegalovirus disease in the era of highly active antiretroviral therapy (HAART)
C Steininger, E Puchhammer-Stöckl… - Journal of Clinical …, 2006 - Elsevier
Cytomegalovirus (CMV) infection was one of the most important opportunistic infections in
HIV-infected patients before the introduction of highly active antiretroviral therapy (HAART),
ie the combination of at least three antiretroviral drugs of different classes. Thereafter, life
expectancy and quality of life increased dramatically with the persistent suppression of HIV
viremia and a significant reduction in incidence of CMV disease. Nevertheless, evidence for
a multitude of direct and indirect effects of CMV on HIV progression is accumulating. Even in …
HIV-infected patients before the introduction of highly active antiretroviral therapy (HAART),
ie the combination of at least three antiretroviral drugs of different classes. Thereafter, life
expectancy and quality of life increased dramatically with the persistent suppression of HIV
viremia and a significant reduction in incidence of CMV disease. Nevertheless, evidence for
a multitude of direct and indirect effects of CMV on HIV progression is accumulating. Even in …