Symptomatic congenital cytomegalovirus infection: neonatal morbidity and mortality
SB Boppana, RF PASS, WJ BRITT… - The Pediatric …, 1992 - journals.lww.com
SB Boppana, RF PASS, WJ BRITT, S STAGNO, CA ALFORD
The Pediatric infectious disease journal, 1992•journals.lww.comAbstract Knowledge of the natural history of symptomatic congenital cytomegalovirus (CMV)
infection in the newborn is essential in order to anticipate complications and assess the
potential benefit from antiviral therapy. To define the disease course we reviewed data on
106 neonates with symptomatic congenital CMV infection diagnosed and managed by the
investigators. Petechiae, jaundice and hepatosplenomegaly were each noted in 70% or
more patients. Microcephaly was noted in 54 of 102 (53%) at birth.
infection in the newborn is essential in order to anticipate complications and assess the
potential benefit from antiviral therapy. To define the disease course we reviewed data on
106 neonates with symptomatic congenital CMV infection diagnosed and managed by the
investigators. Petechiae, jaundice and hepatosplenomegaly were each noted in 70% or
more patients. Microcephaly was noted in 54 of 102 (53%) at birth.
Abstract
Knowledge of the natural history of symptomatic congenital cytomegalovirus (CMV) infection in the newborn is essential in order to anticipate complications and assess the potential benefit from antiviral therapy. To define the disease course we reviewed data on 106 neonates with symptomatic congenital CMV infection diagnosed and managed by the investigators. Petechiae, jaundice and hepatosplenomegaly were each noted in 70% or more patients. Microcephaly was noted in 54 of 102 (53%) at birth.
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