[HTML][HTML] Protein-protein interaction of zinc finger LIM domains with protein kinase C
S Kuroda, C Tokunaga, Y Kiyohara, O Higuchi… - Journal of Biological …, 1996 - ASBMB
The LIM domain comprising two zinc-finger motifs is found in a variety of proteins and has
been proposed to direct protein-protein interactions. During the identification of protein
kinase C (PKC)-interacting proteins by a yeast two-hybrid assay, a novel protein containing
three LIM domains, designated ENH, was shown to associate with PKC in an isoform-
specific manner. Deletion analysis demonstrated that any single LIM domain of ENH
associates with the NH 2-terminal region of PKC. ENH associated with PKC in COS-7 cells …
been proposed to direct protein-protein interactions. During the identification of protein
kinase C (PKC)-interacting proteins by a yeast two-hybrid assay, a novel protein containing
three LIM domains, designated ENH, was shown to associate with PKC in an isoform-
specific manner. Deletion analysis demonstrated that any single LIM domain of ENH
associates with the NH 2-terminal region of PKC. ENH associated with PKC in COS-7 cells …