Evidence for environmental modulation of gametocytogenesis in Plasmodium falciparum in continuous culture.
R Carter, LH Miller - Bulletin of the World Health Organization, 1979 - europepmc.org
R Carter, LH Miller
Bulletin of the World Health Organization, 1979•europepmc.orgWith the introduction of continuous culture of Plasmodium falciparum it has become possible
to study the factors involved in gametocyte production in vitro and thus eliminate the
uncontrollable in vivo variables of the host. The authors have developed a method for
measuring quantitatively the rate of production of gametocytes at any time in such cultures.
The method is based on an estimation of the percentage of ring forms that develop into
stage II gametocytes.
to study the factors involved in gametocyte production in vitro and thus eliminate the
uncontrollable in vivo variables of the host. The authors have developed a method for
measuring quantitatively the rate of production of gametocytes at any time in such cultures.
The method is based on an estimation of the percentage of ring forms that develop into
stage II gametocytes.
Abstract
With the introduction of continuous culture of Plasmodium falciparum it has become possible to study the factors involved in gametocyte production in vitro and thus eliminate the uncontrollable in vivo variables of the host. The authors have developed a method for measuring quantitatively the rate of production of gametocytes at any time in such cultures. The method is based on an estimation of the percentage of ring forms that develop into stage II gametocytes.
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