[HTML][HTML] Identification of DNA-dependent protein kinase as a cofactor for the forkhead transcription factor FoxA2
A Nock, JM Ascano, T Jones, MJ Barrero… - Journal of biological …, 2009 - ASBMB
Forkhead factors are important regulators of animal development and homeostasis. They
are among the earliest to bind quiescent genes, which they activate in conjunction with other
transcription factors. Many liver-specific genes are under the control of FoxA2, a liver-
enriched forkhead protein. Here we confirmed by chromatin immunoprecipitation that FoxA2
is one of the factors bound to the promoter-proximal enhancer of the gene encoding
apolipoprotein AI (a component of high density lipoprotein) and that it functions in synergy …
are among the earliest to bind quiescent genes, which they activate in conjunction with other
transcription factors. Many liver-specific genes are under the control of FoxA2, a liver-
enriched forkhead protein. Here we confirmed by chromatin immunoprecipitation that FoxA2
is one of the factors bound to the promoter-proximal enhancer of the gene encoding
apolipoprotein AI (a component of high density lipoprotein) and that it functions in synergy …