The deficit of pain inhibition in fibromyalgia is more pronounced in patients with comorbid depressive symptoms
JB de Souza, S Potvin, P Goffaux… - The Clinical journal …, 2009 - journals.lww.com
Background On pathophysiologic grounds, fibromyalgia (FM) is characterized by a deficit in
diffuse noxious inhibitory controls (DNIC), but the role of depressive symptoms on these
mechanisms has not been investigated. We hypothesized that the deficit in pain inhibition
would be more pronounced in FM patients with depressive symptoms (FM+ D), relative to
patients without such symptoms (FM− D). Methods Fifty-two women diagnosed with FM
(American College of Rheumatology criteria) and 10 healthy women participated in this …
diffuse noxious inhibitory controls (DNIC), but the role of depressive symptoms on these
mechanisms has not been investigated. We hypothesized that the deficit in pain inhibition
would be more pronounced in FM patients with depressive symptoms (FM+ D), relative to
patients without such symptoms (FM− D). Methods Fifty-two women diagnosed with FM
(American College of Rheumatology criteria) and 10 healthy women participated in this …